Heartworm Protection: Do We Need ProHeart 6?

Written by Jan on June 18, 2008 – 11:06 am

ProHeart 6, a heartworm “preventative” shot providing 6 months of protection against canine heartworms, is back on the market after having been pulled from shelves in 2004 by manufacturer Fort Dodge. More than 5,000 adverse “events,” including hundreds of canine deaths, prompted the FDA to request the drug’s withdrawal. It is being brought back under a “risk minimization action plan” and restricted use program (including vet training and informed consent notification) — an uncommon plan to try to limit damage from the drug.

I wonder, why is ProHeart 6 so indispensable that it must be brought back? There are safer once-a-month heartworm “preventatives.” More importantly, there are countless natural, non-toxic alternatives. (By the way, heartworm drugs do not “prevent” heartworms. They kill them.)

Does a risky six-month remedy have any real value? Not to me as loving guardian to two dogs, and certainly not to the dogs themselves who may suffer potentially lethal adverse reactions. The main value will be to Fort Dodge stockholders and to the vets who benefit from the sale of the product plus the office visit to give the shot.

Before writing about heartworms and other parasites for my book, Scared Poopless: The Straight Scoop on Dog Care, I interviewed three veterinarian-authors and two other holistic vets, and also spent months reading and doing on-line research. Every vet I consulted thought heartworm medications were toxic. Dr. Martin Goldstein, renowned veterinary and author, has written that he sees heartworms as less of an epidemic than the “disease-causing toxicity” of heartworm medicine.

No discussion of this medicine would be complete without a study of the heartworm life cycle. Microfilariae, which grow into heartworms, must be injected into dogs by female mosquitoes. No mosquitoes, no heartworm infestation. Dogs with poor diets, and those suffering from immune system dysfunction, are particularly susceptible.

Most U.S. locales don’t have mosquitoes in cold weather. But even if mosquitoes are present, according to the University of Pennsylvania vet school, microfilariae require sustained periods of weather above 80 degrees and not below 57 degrees (Fahrenheit) to develop to the proper stage to be delivered.

Thus, protection against heartworms is unnecessary year round in many locations. Read more about the mosquito’s life cycle at a website owned by ProHeart manufacturer Fort Dodge, click here. For an unbiased look at nationwide incidences of heartworm and drug adverse reactions, click www.dogsadversereactions.com/moxidectin/heartwormmaps.html

I live in Southern California, an arid area with few heartworm cases. For my own dogs, I use non-toxic alternatives: natural non-toxic bug repellent and keeping the dogs indoors when mosquitoes are buzzing. I also make sure there is no standing water in my yard.

I increase safety by testing my dog’s blood once yearly for heartworm antigens, something also required if they were to take heartworm “preventatives.” If I lived in an area with sustained hot weather and lots of mosquitoes, I’d test twice yearly. Heartworm infestation is generally curable when caught early. The current canine movie star “Benji” is a heartworm survivor.


A follow-up: Still considering giving your dog ProHeart 6 for heartworm protection? ProHearts’ own Client Information Form lists adverse reactions: “These can include (but are not limited to) allergic responses, lethargy (sluggishness), seizures, vomiting and diarrhea, itching at the injection site, fever and, in rare instances, death.” Read the entire Proheart form at (Note: To enlarge the print size, change it to “100%” on the toolbar underneath the word “Help.”)

An article from the FDA worth reading reports “the side effects…anorexia (loss of appetite); lethargy; vomiting; neurologic signs, such as seizures, difficulty walking and reports of blindness; jaundice (a yellowish appearance); and bleeding disorders. Most of these observable clinical signs have occurred within one month of receiving the drug.” www.fda.gov/cvm/PH6QA.htm

To comply with the FDA’s “risk minimization” plan, Fort Dodge is implementing an educational and communication program that will require veterinarians to register with Fort Dodge and complete “in-depth” training as a condition of purchasing ProHeart 6. A letter from the FDA explains vets will also have to “confirm they have completed the in-depth training, read the new label, the conditions of use, the requirements to provide the dog owner with the Client Information Sheet and obtain signed informed consent, record the product lot number in the medical record, and report adverse events. Veterinarians are also advised to obtain baseline history, physical exam, and blood-work parameters prior to administration of the drug to confirm the patient is an appropriate candidate for ProHeart 6.” Read the entire letter at http://www.fda.gov/cvm/ProHeart6AVMA.htm

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In-depth heartworm articles:

Heartworm Medication Part 1: Truths, Omissions and Profits
Heartworm Medication Part 2: Options to Fear-Based Recommendations

Tags: adverse reactions, dogs, FDA, Fort Dodge, heart worm, heartworm, medication, ProHeart 6, side effects, vet, veterinarian
Posted under Heartworms, Pet Meds, Uncategorized | 43 Comments » Email This Post

43 Comments to “Heartworm Protection: Do We Need ProHeart 6?”

  1. ProHeart 6: More About the Drug’s Dangers | Truth4Dogs Says:

    […] Dangers Written by Jan on March 5, 2009 – 5:46 pm This is a follow-up to our first article on Proheart 6.  You might want to read it […]

  2. Pamela Johnson Says:

    So, you would recommend a heartworm test yearly? Would you give heartguard or not? I live in San Diego. How would I find a good holistic vet? Any recommendations?
    Thanks a bunch!
    Pam, Isabelle (husky mix), & bandit (border collie) 🙂

  3. Jean Brudd Says:

    Well said. Thank you so much for this article.

    My dogs were early victims of this poisonous pet product. You can read Tasha, Niki, and Casey’s story under “ProHeart 6 Victims” at http://www.thepetguardian.com.

    The FDA allowed Fort Dodge to back-door this product back onto the market without allowing us, the public, a “voice.” Thank God the U.S. dogs were safe for almost four years while it was off the market.

    The pet-loving public should know: If you get this heartworm “prevention” shot for your dog, you are having literally a pesticide injected into them. Would you do that to yourself or your human baby??

    Within 24 hours, this drug has permeated all organs of the dog’s body. If the dog reacts adversely, there is NOTHING that can be done to remove the drug from his body. The dog is forced to suffer the effects for as long as it’s in his body — if he can live that long. And since the drug is time-released, every month about the time the injection was given, he may suffer those adverse effects again.

    I’m not saying not to give heartworm “prevention” — if you have to in your state — but don’t go the injection route, no matter who the manufacturer may be.

    I cannot emphasize strongly enough: YOU are the expert when it comes to your companion animals, not your vet — and certainly not a drug manufacturer who cares very little about you or your animals. They’re in the business of making money, period.

    BUYER BEWARE! Be safe, not sorry!

  4. Jan Says:

    Jean, I’m glad you liked the article and applaud your advocacy for dogs. I’m so sorry that you, like so many of us, had to learn the truth about pet medications hard way.

    Did you read my recent articles on Heartworms Medications and Pesticide Poisoning? Flea and tick meds are a big problem, too. My newsletter just went out and Heartworms are the first major subject. I’m writing Part 2 of Heartworms to go out soon. I hope you’ve subscribed to this blog so you’ll be notified. Maybe you’ll come back and comment again. Perhaps you’ll also bookmark heartworm articles at Delicious, StumbleUpon or other networking sites. There’s a link on this page. Let’s spread the word!

    Thanks again. And keep up the great advocacy.

  5. Jean Brudd Says:

    Thank you, Jan. Like you, I cannot sit by and watch our animal companions be harmed and die at the hands of these “harmaceutical” companies.

    I have not seen your recent newsletter. Can you please add me to your list for all your mailings? I am going to subscribe by RSS, but truthfully, I’m not sure where these things are going. 🙂

    But I would definitely like to be kept in the loop. I started up my Pet Guardian blog again. Between the two of us — and others, I am sure — we can spread the word even further.

    Thank you so very much for all you’re doing for the animals!

  6. Diana McManus Says:

    I started giving my dog black walnut in his food and it gets rid of over 100 different parasites including heartworms. He was positive for heartworms before I gave black walnut to him and black walnut got rid of the worms.

  7. RayAnn Vaughn Says:

    Hello, My name is RayAnn and my dog’s name is Ghetto. She is a stray that adopted my boyfriend and I. Needless to say she means the world to us and is treated like a child,lol. A year ago this June she was diagnosed with heartworms even though she was on the worm pills. Her new vet wants to give her the 6-month shot and we are leary of giving it to her, especially after reading all the facts about the shot. We dont know what to do.

  8. Jan Says:

    Hi RayAnn. If your dog was on pills but still got heartworm, the manufacturer of the medication should pay for treatment. Is your dog heartworm free now?

    Would I give my dogs the Proheart 6 shot? No. Please read https://www.dogs4dogs.com/blog/2008/06/18/your-dogs-heartworm-protection-do-we-need-proheart-6/ and decide for yourself. Would I stay with a vet who recommended it? No.

    If I were to use a heartworm med, I would make sure that my dog was heartworm free. I would use a medication that treated heartworms only. I would give it every 6 weeks, not monthly. I would give it only during warm months. Please read my other articles about this. You should decide.

  9. Jan Says:

    Ray Ann, I should tell you I’m not a vet. I’m a consumer advocate for dogs and the people who love them.

  10. katie Says:

    My dog, JarJar recieved a 6 month heartworm shot in June 2010. I don’t know if it was ProHeart 6, or if there is something else out there. I had never heard about the shot, and assumed it was safe since it was being offered. 3 weeks later, he started throwing up. He’s been on Cerenia for the last 6 days and hasn’t thrown up again (waiting to see what tonight will hold since the Cerenia has run out).

    I’m finding a lot about negative effects of these shots, but haven’t found anything about the timeline of side effects. Do you think the throwing up could be directly related to the shot?

  11. Jan Says:

    Katie, call Fort Dodge, the manufacturer, and ask them. And find a better vet. The FDA asked Fort Dodge to withdraw it and it was brought back with no product changes, just new warnings. Your vet had a legal and ethical responsibility to tell you about it.

  12. Mark Beason Says:

    I live in the South and I breed/train hunting dogs. Heartworms is a big issue around here. I’ve never used the product mentioned above because when you have more than just a couple dogs it’s not cost efficient. One alternative you might tell your followers about is Ivomec. We’ve been using it for years and haven’t had an issue with it yet. No side effects on the dogs and no heartworms. The doseage is Ivomec 1% solution – 1/10 cc per 10 lbs. of dog weight.

    Note from Jan, blog owner: Thanks for you post, Mark. I am unfamiliar with Ivomec. As always, I suggest anyone wanting to try a new heartworm product clear it with their vet first.

  13. The Truth About Heartworm | The Truth About Everything Says:

    […] Proheart 6 :  severe allergic reactions (anaphylaxis): facial swelling, itching, difficulty breathing, collapse;  lethargy (sluggishness); not eating or losing interest in food; any change in activity level; seizures; vomiting and/or diarrhea (with and without blood); weight loss; pale gums, increased thirst or urination, weakness, bleeding, bruising; rare instances of death. This product was voluntarily withdrawn from the market in 2004 because of deaths but has been reintroduced. Read my post Heartworm Protection: Do We Need ProHeart 6? […]

  14. Lyn Says:

    I have been giving my dog Interceptor every 6 weeks during the summer season following the > 57 degree protocol. In my vet’s appointment today he said that heartworms were becoming medicine resistant and that I should definitely start giving it once per month and also doubling the dose. He could not give me any studies to back this up, but said it was discussed in a recent vet’s convention. Have you heard anything like this?

  15. Jan Says:

    Lyn, I haven’t heard anything about this. In fact, the only alert I have read is about a shortage of the active ingredient of the chemical used to treat a dog that already has heartworm. (See the alert at heartwormsociety.org).

    Your request to have your vet back up this claim with documentation or a source is a good one. Why wouldn’t the vet want documentation or know the exact source? Why not call the company that makes the medication and ask?

    Also, the 6 weeks to 4 weeks change doesn’t make sense to me, but I’m not a vet. Have you read my two articles on heartworm (not just the one on Proheart 6)? https://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/

    Let me know what you find out.

  16. Debby Says:

    Hi Jan – My 100 lb Labradoodle received ProHeart6 in June, on a Monday. He came to the vet for a check up and shots a VERY healthy, active, dog. By Saturday he would not eat his dog food, vomiting, trouble with bowel movements. For the next few months there were several diagnoses i.e. ulcers, upset stomach and full anal glands. This past wknd he got very lethargic. Monday we brought him back to the vet and they found a very large hemangiosarcoma attached to his spleen with internal bleeding. Unfortunately we lost our pet that day.

    When I gave him the ProHeart6 I never knew there was a previous recall or any problem with it. Have you heard of this injection causing cancer?

  17. Jan Says:

    Debby, I’m so sorry for your loss.

    You might check out the info on reactions here: http://www.dogsadversereactions.com/moxidectin/reactions2.html Also, I’d insist that your vet give you the product insert that comes with the product. It should list all reactions, although long-term drug reactions, like cancer, are seldom reported.

    Your vet should certainly have warned you about this medication. The vet owed you a legal duty of full disclosure. I’d give him/her hell for not warning you and for using the medication in the first place. There are many other, safer meds. You don’t say where you live. I hope it was at least a high heartworm area.

    And change vets.

    Again, I send condolences.

  18. Debby Says:

    Thank you Jan. I live in South Florida, yes we are a heartworm area.

    I asked the vet on every occasion we visited them during the few months that Baxter was sick if this illness could be a reaction to the ProHeart injection, and they assured me every time “No”. I was told at that time that the only reaction would have been soreness at the inj site or an upset stomach for a couple of days. NO warnings were given, or information about a previous recall, prior to us giving this injection to our dog.

    I have no problem giving the name of the Vet. We went to Banfield Animal Hospital at a Pet Smart store. Needless to say, we will not go back once we decide to adopt again.

  19. Harriett Wade Says:

    Our dog, Ginger, was two years old when we got her, she was a cocker spaniel. She has never been sick, full of spunk and energy and spoiled rotten. She died November 3, 2011. Two weeks before she died I took her to the vet to get her heartworm shot, she had had one six months before. The vet said it was a lot cheaper than the pill and was perfectly safe. Two weeks later, she was feeling sickly, we took her to the vet and he said she had auto immune deficiency, they kept her, gave her two blood transfusions and other medicines. Four days later she was dead. How do you go from running and playing ball one minute to almost dead the next. I think it was the heartworm shot that killed her. They said her eyes and gums were yellowish and also her blood. What do you think? We have just been heartbroken over this.

  20. Jan Says:

    Harriett, I’m so sorry for your loss.

    It’s my guess that your vet just doesn’t want the responsibility of having given a potentially dangerous shot, with well documented adverse reactions, to your dog. Please get a copy of your dog’s file and ask your vet for a copy of Proheart’s product insert. There is no reason why you shouldn’t have it. You need to see all the known reactions. Then call the manufacturer of Proheart 6. Tell them what happened and say you want them to pay your bills.

    Also check out reactions here: http://www.avma.org/onlnews/javma/sep08/080901c.asp You’ll probably also want to read this: http://www.avma.org/onlnews/javma/jul08/080715m.asp

    Your vet should have told you that Proheart had so many problems that it was withdrawn from the market. If not, you should complain to your stain veterinary board.

    I wish you well in your endeavors.

  21. Pamela Magadance Says:

    Hi, I am new to knowing about your website. I have a dog with cancer. Have been doing tons of research. Fortunately, I have a great holistic vet. I was interested in reading about Ivomec for heartworm. I have used it for several years. My vet agrees. I think that the dose recommended by the person who wrote to you is a little high, IMO, but not dangerous. I wish you would check it out with your vet. If you agree, then you could tell everyone about it. I think it’s a great alternative to the many toxic products out there. It just treats heartworm and doesn’t have a lot of other stuff in with it.

  22. Jan Says:

    Pamela, Ivomec is designed for cattle. It is cheap Heartgard.

    My dog Jiggy has cancer. Nothing could make me give him heartworm meds. I do not live in an area where heartworm is a problem, but I would want nothing but health building products going into my dog. I would test several times a year for heartworm as an alternative to medication. Please read my second article on heartworms for more tips.

    I know few holistic vets who prescribe heartworm meds. In fact, I know none. Are you sure your vet is truly holistic? It’s a label many vets are using for promotional value. I don’t know your vet, but I’d check if I were you. Is she/he on the http://www.holisticvetlist.com? Does this vet offer many natural modalities?

    Just my opinion. But would you consume poison if you had cancer?

  23. Kelly Says:

    I work at a vet clinic and have experienced the heartbreak of treating animals with heartworm infections – even though I live in a very dry, high-altitude climate. It is so sad that some people (including the author here) believe that if your dog contracts heartworms – you can just treat it. There is a treatment for dogs (no such treatment available for cats who should also be on preventative) but it is expensive and deadly. Dogs undergoing heartworm treatment must be confined for six weeks for the treatment (jumping, running, etc. can cause pieces of the worms to break off which could cause a pulminary embolism and death). Those who survive treatment often suffer lifelong damage to their organs from this horrible disease.
    Most of the heartworm preventatives (it does prevent heartworm infection in pets – no it does not prevent them being exposed to the organism) often prevent intestinal parasite infections as well. This is especially important because most of these can be passed to us – and our kids. Roundworms cause blindness in children every year. So sad that could be prevented if all pets were on prevention!

    There are pets who have gotten sick and even died after receiving heartworm prevention. There is no evidence this is caused by any of the heartworm preventatives – not even ProHeart. We live in a sue-happy society. Proheart 6 was not pulled in other countries and they even use 12 month versions elsewhere. Just like red m&ms did not really cause cancer – but they had to pull it due to rumors – this happens with many medications. Unfortunately pets sometimes get sick. Sometimes they have received a medication before they got sick. Correlation does not equal causation.

    Please protect your pets and your family from parasites. Dogs exposed to heartworms have nearly a 100% infection rate if not on preventative. We have all had a mosquito indoors – all pets need prevention.

  24. Melissa Says:

    Thank you to Kelly (comment 23)for your post. It is disturbing to see so much misinformation in many of the previous comments made. Everyone would do well to get more facts from the veterinary community that is constantly striving to provide the most comprehensive and up-to-date information on heartworms (preventative and treatment included)..check out heartwormsociety.org…it is the most complete source out there and has a LOT of tried and true information backing it (these veterinarians are NOT being paid by the companies making heartworm products…most if not all are working for little in universities and veterinary teaching hospitals). The majority of veterinarians are NOT the bad guys…if you have ever seen dogs being affected by heartworm disease, you would be more inclined to consider the most effective options for prevention.

  25. Sarah Says:

    Just wanted to let you know FortDodge no longer makes Proheart. Pfizer is now distributing it.

  26. Realistic Says:

    I do understand everyones concerns and I can empathize with ones feelings. And I am not here to judge, but to share my comments as well about Pro Heart 6. I have 3 wonderful & beautiful babies of my own a 3yr. old Golden,a 3yr. old Mix & also another mix whose a miniture Daxson golden retriever only 7 months old. Both of My 3yr olds been on Pro Heart when they turned 1 and they both been safe and fine since, they have’nt shown no side effects of this medication. And they continue this treatment, now however my little one does not receive this treatment under the circumstances that he be treated correctly first with a medication that will be suitable. Until his wight and size are well stable to maintain along turning to the right age only then my Vet will recommend that it will be alright for my little one to be on Pro Heart 6. On the other hand my Vet have been giving the right amount of dose to both of my 3yr. olds. So far my pets are Healthy and Living the Good life. I’m not saying it’s safe & I’m not saying it’s not, all I’m saying make sure that you have a Vet that “knows” what they are doing and not just Think that your baby will be fine before you know it they just got you on a line & hook to make a quick buck for selling another company their product. Which my Vet made sure when was the “RIGHT” TIME & what was “RIGHT” DOSE. Because that’s what usually happens when the pet was mis given the amount of dosage that would cause the animal to react too the side effects and which cause the animal to overdose. Know Your Vet, Be Cautious & Always Ask Questions, Make Sure That You Know First Hand that Your Vet “KNOWS” what is the RIGHT amount of dosage your pet is getting. Then ask “for proof” if he/she is unable to give u proof but eager in giving you the sale pitch on the other hand, I recommend that you pass up on it.
    What is the Proof you ask? Well he/she will tell you how many clients they have whose under their care that haven’t had any mishaps. meaning “NONE”! If your Vet is HONEST they will tell you.
    But what they won’t tell you is “the truth what went wrong” but hide behind the people who produce it. And that’s the TRUTH!

  27. Jan Says:

    Realistic, are you really? I would never risk my dog’s health with a product that was “voluntarily” pulled from the market because of so many bad reactions. And that was brought back for monetary reasons with lots of warnings?

    And why treat at all during the winter when it’s all but impossible to contract heartworms? Have you read https://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/

    Clearly you trust your vet. I trusted my dog with a vet’s vaccination recommendation. That led to 12 years of heartache and vet bills. No problem for him. I suspect he maintains there is no such thing as a vaccine reactions. But there is no such thing as a safe drug. Just because your dogs haven’t had reactions and your vet hasn’t seen reactions doesn’t mean they won’t happen tomorrow.

    Good luck.

  28. Holly Says:

    This product has been used in Australia for many years under the name proheart 12, twice the dose with 1 injection. This is not a vaccine. The dogs in Australia didn’t have the problems that the dogs here have had with the same drug.

  29. cathy Says:

    Hi Jan:
    Recently found your website. Love it. Thanks for all of your great info. I am so confused about what to do for our 2 year old pekingnese shihtzu. We had him on Trifexis but he is having a problem taking this pill. Our vet wants to change him to ProHeart and a flea/tick topical. We never liked the topical, as we just hug him too much – we didn’t want the chemical all over. I was thinking about Revolution topical that covers everything so we wouldn’t need the injection. Just don’t know what to do. I am at a real standstill. Trying to do my research but nothing seems good enough. Do you have any suggestions for me. We love our baby too much. I need help!!! Thanks, Cathy 🙂

  30. Jan Says:

    Cathy, thanks for the nice words about my website. I hope you’ll check out my new http://www.truth4pets.org/ as well.

    Re heartworms, everything I know is in this 2 part article: https://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/

    Re flea meds, a really healthy dog may not need meds. Feed the best and vaccinate only as absolutely necessary. http://truth4pets.org/question-before-vaccination/ Also, make sure you really have a flea problem.

    There have been a lot of problems reported with Trifexis, so it’s good your dog is off it. Remember that this stuff is all toxic. Use the product with the fewest ingredients, use a half dose, and give only every 6 to 8 weeks or as necessary. I would try Advantage or Revolution, not Advantix, but they are all potentially harmful. There’s a good spray made by Evolution that’s worth a try.

    Good luck.

  31. Hero Cat Saves Boy from Dog Attack Says:

    Great post. I was checking constantly this blog and I’m impressed!
    Extremely helpful info particularly the last part 🙂 I care
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  32. Heartworm Medication Part 2: Options to Fear-Based Recommendations | Dogs Naturally Magazine Says:

    […] Proheart 6 :  severe allergic reactions (anaphylaxis): facial swelling, itching, difficulty breathing, collapse;  lethargy (sluggishness); not eating or losing interest in food; any change in activity level; seizures; vomiting and/or diarrhea (with and without blood); weight loss; pale gums, increased thirst or urination, weakness, bleeding, bruising; rare instances of death. This product was voluntarily withdrawn from the market in 2004 because of deaths but has been reintroduced. Read my post Heartworm Protection: Do We Need ProHeart 6? […]

  33. The Truth About Heartworm Worth The Read! | rrruffhouse Says:

    […] Proheart 6 :  severe allergic reactions (anaphylaxis): facial swelling, itching, difficulty breathing, collapse;  lethargy (sluggishness); not eating or losing interest in food; any change in activity level; seizures; vomiting and/or diarrhea (with and without blood); weight loss; pale gums, increased thirst or urination, weakness, bleeding, bruising; rare instances of death. This product was voluntarily withdrawn from the market in 2004 because of deaths but has been reintroduced. Read my post Heartworm Protection: Do We Need ProHeart 6? […]

  34. Beth Says:

    I found your web page today while I am searching for info on Proheart 6 and the time span it really covers. I didn’t have any idea about these recalls!! Just today I had 2 of my dogs in for their yearly HW tests and Proheart 6 injections. They were over due by just under 1 month and my one Lab came back (weak) positive!!! The vet said in other countries it was proven to last longer than 6 mths. So I questioned about what is the false positive rate of this injection? The vet didn’t have an answer, but we drew more blood to be sent out and tested for verify one way or the other. Vet also looked at a sample under the scope and didnt see anything… I will know tomorrow of these results.
    I won’t be using Proheart 6 ever again… but my immediate questions I am searching for answers is how much longer than 6 mths in other countries has Proheart 6 really lasted and what is the false positive percentage?
    My 3 Labs are all indoors and only go out when I go out with them (they’re not left alone in yard at all). I religiously use every month thru out the year Advantix II and I spray yard for mosquitos. They also are on HW preventative thru out the the year. I have owned Labs for 30 years and this is the first time EVER I’ve had one come up positive for HW!! Thank you in advance for whatever info or advice you can give on this matter

  35. Jan Says:

    Beth, I have no answer to your Proheart question. Why not call or write the manufacturer? They need to know what happened in any event.

    Know that medications don’t have clocks. They do not become ineffective exactly on time. The time given is just the duration of testing. That is, if they only test for 6 months, that’s their guarantee.

  36. Patsy Linton Says:

    I did not know the dangers of proheart 6 .the vet gave my chihuahua the shot about a week ago. she has not been playful since and lays around a lot. Please tell me there is somthing I can do to keep her from getting worse.she is eating good just dont feel like doing the things she did before the shot. I know it takes 6 months to get this out of her system and dont want her to get worse. Don’t know how I can stand it if I lost her…please help….thank you

  37. Ajayallvetmed Says:

    Added to Feed Burner as well. More than likely I’m likely to bookmark your blog . You amazingly have amazing stories. Thanks a bunch for revealing your webpage

  38. Kathy Wilson Says:

    Patsy, I just now saw this site and your post. I am too,late to give advice but I almost lost my shih tzu to this shot. It was the longest and hardest 6 months of my life! I hope your dog has done well. At this time the 6 months is over for you. I hope your outcome was good.

  39. Scott Malone Says:

    Like Many people I wish I would have read this earlier. Just two days ago I took my Newfoundland to the vet for his heart worm shot. He was a big healthy dog over 220 pounds. He went into a form of anaphylactic shock on the way from the vets. I can’t describe how horrible it was trying to give him mouth to mouth while we rushed him back to the vet just to have him die in my arms. I live in Louisiana where mosquitoes are a problem. I have had dogs with heart worms and I thought I was doing the right thing to protect my dog. If I would have read anything about the potential risk I doubt I would have had him injected. I trusted without knowing the risk and I have the guilt of feeling that my ignorance may have cost me my beloved best friend.

  40. Jen Says:

    What Vet School did you graduate from?

  41. Jan Says:

    I do not pretend to be a vet, nor do I profit from selling heartworm meds. I just try to help people make informed decisions. I don’t care what their decisions are. I wish all vets would offer complete information re pros and cons and others wouldn’t have to do research for the public.

  42. Harless Black Says:

    We just recently lost our healthy yorkie to what we believe to be a adverse reaction lt pro heart 6.we trusted our vets recommendation for us it’s too late, never again?
    Looking to see if any class action suites are being filed .
    I have reported to the manufacture and to the FDA.
    Should never have happened. The report comes back this Thursday. But truth will probably lay never be told,all around a horrible experience .

  43. Jan Says:

    Harless, I’m not aware of any suit. You’ll have to poke around online. Are you having a necropsy done to prove cause of death?

    Most vaccine reports go to the USDA but I’m not sure about Proheart. And Congress protects vaccine makers from liability. If Proheart did cause death, ask them to pay for your expenses and maybe the “value” of your dog. Of course, they can never repay you, but it’s worth a try to punish them a little.

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