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	<title>Truth4Dogs &#187; Heartworms</title>
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	<description>Exposing Myths, Lies and Outdated Information Affecting Dogs</description>
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		<title>Heartworm Medication Part 2: Options to Fear-Based Recommendations</title>
		<link>http://www.dogs4dogs.com/blog/2009/06/16/heartworm-preventative-options/</link>
		<comments>http://www.dogs4dogs.com/blog/2009/06/16/heartworm-preventative-options/#comments</comments>
		<pubDate>Tue, 16 Jun 2009 07:01:48 +0000</pubDate>
		<dc:creator>Jan</dc:creator>
				<category><![CDATA[Heartworms]]></category>
		<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[dog]]></category>
		<category><![CDATA[dog heartworm]]></category>
		<category><![CDATA[heart worms]]></category>
		<category><![CDATA[heartworm]]></category>
		<category><![CDATA[heartworm disease]]></category>
		<category><![CDATA[heartworm in dogs]]></category>
		<category><![CDATA[heartworm medication]]></category>
		<category><![CDATA[heartworm medicine]]></category>
		<category><![CDATA[heartworm preventative]]></category>
		<category><![CDATA[natural cures]]></category>
		<category><![CDATA[natural preventatives]]></category>
		<category><![CDATA[prevention]]></category>
		<category><![CDATA[reactions]]></category>
		<category><![CDATA[Safeheart]]></category>
		<category><![CDATA[Safety]]></category>
		<category><![CDATA[side effects]]></category>
		<category><![CDATA[split dose]]></category>

		<guid isPermaLink="false">http://www.dogs4dogs.com/blog/?p=396</guid>
		<description><![CDATA[Heartworm preventation methods should depend on your dog’s location, lifestyle, travel schedule, health, climate and the time of year. Learn about adverse reactions to popular medications plus ways to prevent infection naturally and with lower doses. ]]></description>
			<content:encoded><![CDATA[<p style="text-align: left;"><span style="color: #cf0000;"><strong>If you haven’t read Part 1 of this article, “<a title="Read this first" href="http://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/ ">Heartworm Medication: Truths, Omissions and Profits</a>,” please read it now <em>unless you completely understand how and when heartworms are transmitted</em>. </strong><span style="color: #000000;">Click the link at that article&#8217;s end to return here.</span></span><span style="color: #cc0000;"><span style="color: #000000;"> </span></span><span style="color: #cc0000;"><span style="color: #000000;"> </span></span></p>
<p style="text-align: left;"><span style="font-size: 9pt; line-height: 115%;"><img class="size-full wp-image-227  alignnone" title="heartwormincidencemap2-sized" src="http://www.dogs4dogs.com/blog/wp-content/uploads/2009/04/heartwormincidencemap2-sized.jpg" alt="heartwormincidencemap2-sized" width="603" height="378" /></span></p>
<p class="MsoNormal" style="margin: 0in 0in 10pt;"><a></a><a href="http://www.heartwormsociety.org/download/Heartworm-Incidence-Map.pdf"></a></p>
<p><span style="color: #000000;">A Heartworm Society news release states:  “By giving heartworm prevention every month, forgetful pet owners will have their pets protected when they need it most.”  But doesn’t that also mean they get it when they need it <em>least</em>? Or need it not at all? Are <em>you</em> a &#8220;forgetful&#8221; owner?</span><span id="more-396"></span></p>
<p>In this part of my heartworm series, we&#8217;ll discusses informed decision-making, and suggests ways, <em>if you want them</em>, to limit or eliminate heartworm drugs. I am a researcher and holistic health advocate, not a vet.  Please learn the facts then discuss with your vet the appropriate course given your dog’s location, lifestyle, travel schedule, health, climate and the time of year.  Expect an open-mind and respect from your vet, or find another vet.  Just as with <a title="Eliminating Unnecessary Shots" href="http://www.dogs4dogs.com/blog/2009/04/22/no-unnecessary-dog-shots/">vaccination</a>, “one size fits all” is outdated, profit-driven, lazy medicine.</p>
<p>Take a look at the map above, courtesy of the  Heartworm Society.  <a title="Make sure you read Part 1" href="http://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/">Part 1</a> of this article demonstrated that transmission is heat and mosquito dependent.   As expected, dark areas of the map, which show the most heartworm cases per clinic, are found in the hot, humid Southeastern US, especially the Atlantic and Gulf coasts and Mississippi Delta.</p>
<p>Don&#8217;t let the map scare you. If published seasonally, map colors would pale significantly during cool months. Also remember that you&#8217;re seeing generalities, not specifics.  A clinic near a rural pond will likely have many cases while an urban clinic 15 miles away may have a much lower incidence.  Maps are general.  Determine your own microclimate. Ask your vet how many cases of heartworm infection he/she treated in the past year.  Also ask if he/she treats all positive cases, or just those with advanced infestation. If the vet doesn&#8217;t keep detailed records, that should tell you something.</p>
<p>Conservative start/stop maps from heartworm researchers Drs. David Knight and James Lok (in &#8220;Seasonality of Heartworm Infections and Implications for Chemoprophylaxis&#8221;) show only two areas requiring year round heartworm meds: the southernmost areas of Florida and Texas.  Houston, New Orleans and similar areas are shown requiring meds for 9 months.  Other states range from 3-7 months. The Drs. wrote:  <span style="color: #cc0000;"><strong>“For nearly 80% of the states, the potential for heartworm transmission is limited to 6 months or less.”</strong></span> Here are <a href="http://www.citadeltm.com/Heartworm.html">start/stop maps</a> for the US and <a href="http://www.heartworm-hotline.org/ ">California</a>. Again, they are very conservative and very general. Do your own research and be specific.</p>
<p>The Heartworm Society warns that heartworm infectations are getting worse.  <a href="http://veterinarynews.dvm360.com/dvm/Veterinary+news/Heartworm-spreading-in-the-United-States/ArticleStandard/Article/detail/587440">DVM Magazine</a>, a magazine for vets, reports that recent results do show a rise in the number of positive cases per clinic in 31 states. DMV reports: “The reasons likely are multifactorial, including increased heartworm testing, increased client base per clinic or even climate trends.”</p>
<p><span style="color: #cf0000;"><strong>Does Year Round Medicating Bring Extra Protection?</strong></span></p>
<p>Applying suncreen at night is useless. So is taking heartworm medication when climate conditions prevent transmission.  Only a small percentage of climes permit year-round transmission. Everyone else is unnecessarily subsidizing drug companies and &#8220;preventatives&#8221; sellers <em>and, more importantly,</em> exposing their dog to unnecessary risks.</p>
<p>Two exceptions: 1) &#8220;Forgetful&#8221; and irresponsible pet parents who won’t begin the medication on time <em>or</em> build their dog&#8217;s natural immunity <em>might </em>want to medicate year round, although that means they have to remember to give meds every month.  2) If your dog contracts heartworms within a few years of beginning medication &#8230; <em>and </em>you can show you gave meds year round &#8230; <em>and</em> your dog had the required blood tests (2 or 3),  you may benefit a little financially because drug companies will pay for dog&#8217;s treatment. (Read the <a href="http://www.1800petmeds.com/guarantee_info.jsp  ">guarantee</a> terms published by an on-line seller.)<strong> </strong></p>
<p><span style="color: #cc0000;"><strong> Are Heartworm Preventatives Safe?</strong></span></p>
<p><em>You&#8217;ve seen those scary photos of worm-strangled hearts, right? Shouldn&#8217;t you give meds year round just in case? Isn&#8217;t safe better than sorry? </em></p>
<p>But is that harmless little pill or yummie medical &#8220;brownie” really safe?  <span style="color: #cc0000;"><strong>No drug is completely free of risk and  adverse reactions. </strong></span> I can find no <em>long-term</em> studies regarding cancer risks and organ damage for dogs receiving heartworm insecticides year round (or even for a few months). Such a study would be difficult to conduct and very expensive.  Who would fund such a study &#8211; or publish any negative findings?</p>
<p>One clue to the possibility of adverse reactions should be label warnings: call <em>your doctor immediately if ingested; keep away from children; wash your hands immediately after use&#8230;.</em> How can medication be good for dogs but so dangerous for <em>you?</em></p>
<p>Another question: <strong><span style="color: #cc0000;">is your dog healthy enough for these medications? </span></strong>The &#8220;Heartworm Prevention&#8221; page of the <a href="http://www.healthypet.com/faq_view.aspx?id=194 ">American Animal Hospital Association </a>states: &#8220;Healthy kidneys and normal liver functions are essential in metabolizing most medications.&#8221;  Many dogs, including my Jiggy, do not have healthy organ function. I wonder how many unhealthy animals are nevertheless on meds?</p>
<p><strong><span style="color: #cc0000;"><strong>Adverse Reactions to Heartworm Medications</strong></span></strong></p>
<p>With any drug, study FDA and manufacturer information <em>before</em> medicating.</p>
<p>These adverse reactions have been reported to the FDA by manufacturers.  (Click the links for more information; write or call manufacturers with any questions). Terms you might not understand include ataxia (gross lack of coordination of muscle movements), pruritus (itchy dermatologic condition), urticaria (hives), mydriasis (excessive pupil dilation), and erythema (skin redness). Other terms should be self-explanatory.</p>
<p><a title="See the reactions" href="http://www.drugs.com/vet/heartgard-tablets-for-dogs.html ">HEARTGARD</a> and <a href="http://www.triheartplus.com/product_information.html">TriHeartPlus</a> (ivermectin): Depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia staggering, convulsions and hypersalivation. <a href="http://www.interceptor.novartis.us/dog/en/label.shtml ">INTERCEPTOR</a> (milbemycin oxime) reports the above reactions <em>plus</em> weakness.  <a href="http://www.sentinelpet.com/product_insert.pdf">Sentinel</a> (milbemycin oxime) reports vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation and weakness.</p>
<p><a href="http://www.revolution4dogs.com/PAHimages/compliance_pdfs/US_EN_RV_compliance.pdf">REVOLUTION® </a>(selamectin), Topical Parasiticide For Dogs and Cats: pre-approval reactions of vomiting, loose stool or diarrhea with or without blood, anorexia, lethargy, salivation, tachypnea, and muscle tremors. Post-approval experience included the above plus pruritis, urticaria, erythema, ataxia, fever, and rare reports of death and seizures in dogs.</p>
<p><a href="http://www.proheart6dvm.com/docs/client_info_03_09.pdf">Proheart 6 </a>:  severe allergic reactions (anaphylaxis): facial swelling, itching, difficulty breathing, collapse;  lethargy (sluggishness); not eating or losing interest in food; any change in activity level; seizures; vomiting and/or diarrhea (with and without blood); weight loss; pale gums, increased thirst or urination, weakness, bleeding, bruising; rare instances of death. This product was voluntarily withdrawn from the market in 2004 because of deaths but has been reintroduced. Read my post <a title="Permanent Link to Heartworm Protection: Do We Need ProHeart 6?" rel="bookmark" href="http://www.dogs4dogs.com/blog/2008/06/18/your-dogs-heartworm-protection-do-we-need-proheart-6/">Heartworm Protection: Do We Need ProHeart 6?</a></p>
<p>For any other brand, research the product or its <span style="text-decoration: underline;">active</span> ingredient <em>before</em> even thinking of administering it.</p>
<p>Also, never give any meds without first learning if any vitamins, minerals, herbal products or drugs interact negatively with the medication. Note age restrictions. <em>Most importantly,  learn what symptoms alert you to a reaction. </em>Important note: Collies, Australian Shepards and related breeds have a sensitivity to <a href="http://www.vetmed.wsu.edu/depts-vcpl/">ivermectin</a> (Heartgard and others).</p>
<p>Beware any website or person professing the absolute safety of <em>any</em> medication.  I&#8217;d like adverse reactions for pet medications to be included in all TV ads, as they are for meds for humans &#8212; but I don&#8217;t expect it.</p>
<p class="MsoNormal" style="margin: 0in 0in 10pt;"><strong><span style="font-size: 10pt; background: yellow; color: black; line-height: 115%; font-family: &quot;Georgia&quot;,&quot;serif&quot;; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-highlight: yellow;">Reporting Adverse Events</span></strong><span style="font-size: 10pt; background: yellow; color: black; line-height: 115%; font-family: &quot;Georgia&quot;,&quot;serif&quot;; mso-highlight: yellow;">:</span> Call your veterinarian immediately if you suspect a reaction to this or any other drug.  Discuss alternatives and treatment and make sure the reaction is recorded in your dog&#8217;s file. The AVMA says : &#8220;&#8230; notify the US Food and Drug Administration (FDA) by contacting the manufacturer. The FDA requires that manufacturers of FDA-approved drugs forward adverse event reports to the agency.&#8221;   Is the fox is guarding the hen house? Ask your vet to report the reaction, then <em>follow up </em>and make sure your vet did it. Under-reporting is common. (An estimated 99% of adverse reactions go unreported according to the FDA.) Click here for <a href="http://www.fda.gov/AnimalVeterinary/SafetyHealth/ReportaProblem/ucm055305.htm">FDA reporting instructions</a>.</p>
<p><span style="color: #cc0000;"><strong>Tests for Heartworm Infection<br />
</strong></span><br />
Heartworms can, and should, be detected by a simple blood test before administering medication.  The <strong><span style="color: #cc0000;">antigen </span></strong>test detects an adult female worms at least 5-8 months old. The <a href="http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/11300.htm ">Merck Veterinary Manual </a>says: &#8220;The antigen detection test is the preferred diagnostic method for asymptomatic dogs or when seeking verification of a suspected HW infection.&#8221;</p>
<p>Microfilariae (babies) in the blood are detected by a different blood test.  These show exposure, but do not detect  female adults (potential breeders).  <a href="http://www.vetinfo.com/dencyclopedia/dehwtest.html"><em>Antibody tests</em> </a>(as opposed to <em>antigen</em> tests) are <span style="text-decoration: underline;">not </span>preferred because they indicate only that the dog has been exposed to heartworms at some time in his or her life, even if the worms subsequently died.</p>
<p>If you plan to give &#8220;preventatives,&#8221; test before beginning medication, preferably within a month of when daily temperatures consistently climb above 57˚ F.  Read more at the <a href="http://www.heartwormsociety.org/article_11.html">Heartworm Society</a> Serology section.</p>
<p>If you&#8217;re <em>not</em> going to use meds, homeopathic veterinarian <a href="http://www.homeovet.net/content/lifestyle/section4.html">Jeff Feinman </a>wrote me that he advises semi-annual testing when not using preventatives.  My own vet, <a href="http://www.healinghope.net">Tamara Hebbler</a>, agrees.  Testing twice yearly helps you catch disease early when it&#8217;s easier to treat. Dr. Martin Goldstein in <em>The Nature Of Animal Healing </em>says: “Only a small percentage of dogs who get heartworm die of it, especially if they&#8217;re routinely tested twice yearly for early detection. Even in untreated dogs, after a period of uncomfortable symptoms, the adult worms die&#8230;.”</p>
<p>Did you know that the latest canine movie star &#8220;Benji&#8221; was found in a shelter, infected with heartworms? Benji was treated successfully and went onto canine fame and a healthy life.</p>
<p>Heartworms, like other parasites, don&#8217;t become life threatening quickly or inevitably. It takes at least 5 months, and more often 7-8 months, for a baby to grow to a reproducing adult &#8212; presuming the dog&#8217;s immune system doesn&#8217;t intervene.  Also, adult males <em>and </em>females must both survive to breed.</p>
<p><strong><span style="color: #cc0000;"><em>Important Note </em></span></strong>If your dog&#8217;s antigen test comes back <em>positive</em>, holistic vet <a href="http://www.healinghope.net">Tamara Hebbler</a> suggests that <strong>before you rush into treatment with harsh, poisonous drugs, you should get a cardiac ultrasound to determine the extent of the infestation</strong>. Heartworms, like other parasites, often live with their hosts without ever causing a dangerous problem.  It&#8217;s quite common for animals in the wild to live entire lives with heartworms. (If worms always killed dogs, they&#8217;d soon run out of hosts.)  Unless heartworms are re-introduced by another infected mosquito, the adults and their babies will eventually die off.</p>
<p><span style="color: #cc0000;"><strong>When Should You <em>Start</em> Administering Meds &#8212; If You&#8217;re Going To?<br />
</strong></span><br />
Remember, you kill heartworm babies after the fact. You can only “prevent” them by avoiding mosquitoes.  (You can also kill them with a healthy immune system.) This means starting meds 30-45 <em>after </em>the weather warms and mosquitoes appear. Also, Washington State University warns, “If your pet travels to heartworm areas, prevention needs to be administered within 30 days of exposure to infected mosquitoes. Adult dogs (older than 6 mos.) need to be tested before starting preventative.&#8221;</p>
<p><a href="http://www.mashvet.com/">Dr. Margo Roman</a>, an integrative vet from in Massachusetts, <a href="http://drdomore.org">documentary film maker </a>and Founder of the first-ever <a title="Expo preceding the event for Holistic Vets" href="http://ihpe.info/">Integrative Health Pet Expo </a>in Massachusetts this fall, tells me she begins medication six weeks after sees mosquitoes. This allows 2 weeks for the microfilariae (baby heartworms) to mature  inside a mosquito to the infective stage and be transferred to a dog, plus 30 days additional days covered by the medication working backwards to kill those babies.</p>
<p><span style="color: #cc0000;"><strong>When Should You <em>Stop</em> Heartworm &#8220;Preventatives&#8221;?</strong></span></p>
<p><span style="color: #000000;">Dr. Roman recommends stopping meds after the first frost for people living in an area with cold winters.  In other areas, vets recommend stopping 30-45 days after weather is consistently below 57 F degrees and you see no mosquitoes. See Part 1 of this article, and the start/stop maps, for more details.</span></p>
<p><span style="color: #cc0000;"><strong>What Brand Should You Use?</strong></span></p>
<p><span style="color: #000000;">Consumers often think that &#8220;preventing&#8221; as many parasites as possible with one product is a bargain &#8212; and ultimately safer for the dog.  But why expose your dog to additional, unnecessary toxins?  Most holistic vets will tell you to protect against <em>only</em> those pests (and diseases) your dog is likely to encounter.  To see which products do what, see the “preventatives” comparison chart at <a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=15&amp;A=488&amp;SourceID=">Veterinary Partner</a>. </span></p>
<p><span style="color: #000000;"><a href="http://www.veterinarypartner.com/Content.plx?P=A&amp;C=15&amp;A=488&amp;SourceID"></a></span><span style="color: #cc0000;"><strong>***<em>Low Dose</em> &#8220;Safeheart&#8221; Medication Approved by the FDA</strong></span></p>
<p>More than a decade ago &#8212; on June 4, 1998 &#8212; the <strong><span style="color: #cc0000;">FDA approved a 1/5 dose version of Interceptor heartworm medication, a product called Safeheart. </span></strong> This expensive field trial was conducted and the dosage approved  &#8212; but inexplicably <em>the product was</em> <em>never marketed in the U.S</em>.<em> </em></p>
<p>To duplicate the Safeheart heartworm &#8220;prevention&#8221; method &#8212; which you can&#8217;t buy &#8212; you have split the Interceptor dose into quarters. Check with Interceptor first, and ask your pharmacist or vet how to do this accurately.  The recommended once-a-month dosage is 0.1 mg of milbemycin oxime per kg of body weight (0.05 mg/lb). (Interceptor&#8217;s regular dose of dosage is 0.5 mg milbemycin oxime per kg of body weight.) Print the FDA&#8217;s <a href="http://www.fda.gov/AnimalVeterinary/Products/ApprovedAnimalDrugProducts/FOIADrugSummaries/ucm054862.htm">Safeheart report </a>and take it to your vet for your prescription and additional instructions.</p>
<p><em>Note: At this dose, only heartworms will be treated with the Safeheart method, not other worms or fleas.</em></p>
<p><span style="color: #cc0000;"><strong>How Often Should You Give Meds?</strong></span></p>
<p>In his important book <em>Homeopathic Care For Cats and Dogs</em>, veterinarian Don Hamilton says of heartworm:  “In dogs the &#8220;monthly&#8221; preventives are effective if given at six week intervals, and possibly even at seven- or eight week intervals&#8230;.&#8221;  Author/veterinarians Richard Pitcairn and Allen Schoen told us essentially the same thing when we were researching our book <a title="Scared Poopless: The Straight Scoop on Dog Care" href="http://www.dogs4dogs.com/">Scared Poopless</a>.  If you opt for this “less is more” treatment with &#8220;preventatives,&#8221; mark dosing dates on your calendar and don’t miss them.</p>
<p>The vets at <a href="http://www.holisticvetcenter.com/heartworm-disease.htm">Holistic Vet Center</a> say:  “… monthly heartworm preventatives are actually 100% effective if given every 45 days and 99% effective if given every 60 days.”</p>
<p>I presume that the monthly schedule was designed for the ease of remembering when to give meds.  However &#8230; giving meds monthly rather than every 45 days requires more doses  &#8211; and offers more opportunities for adverse reactions.  For someone medicating year-round, that&#8217;s 4 fewer doses per year.</p>
<p><span style="color: #cc0000;"><strong>Are There Natural Heartworm Preventatives?</strong></span></p>
<p>Mosquito control is the ultimate natural preventative.  No mosquitoes, no heartworms.  Control mosquitoes by eliminating standing water and staying indoors at dusk and dawn. Use bug spray (marked safe and non-toxic for animals and children). Buy bug zappers. (All these are good ideas for human protection from mosquito-borne diseases as well.)</p>
<p>Is mosquito control 100% effective? No, but  <a href="http://www.mosquito.org/mosquito-information/control.aspx">Mosquito.org </a>has some great tips. (Note: one study showed that a full moon increased mosquito activity by 500%.)  Find more information on <a href="http://news.ucanr.org/newsstorymain.cfm?story=751">controlling mosquitoes </a>in this University of California report.</p>
<p><em>What do I do?</em> Well, for me, the choice was easy. I live in So. California. I rarely see mosquitoes. My dogs spend most of their time indoors. Nights are invariably cool.</p>
<p>With the advice of two local vets, I decided to protect my own dogs (both of whom have health challenges) against the toxicity of heartworm &#8220;preventatives&#8221; rather than protect against an unlikely infection. I use non-toxic alternatives like mosquito control, an excellent diet and no drugs unless they&#8217;re absolutely unavoidable. I increase safety by testing blood twice yearly. I haven’t used “preventatives” for five or six years and my dogs remain heartworm free. This is my personal decision.  I am not a vet.</p>
<p>If I lived in a mosquito-heavy area, however, I might do much the same. I would determine local risks and would consult a local holistic vet to get help preventing heartworms naturally. I would control mosquitoes and test blood twice or more yearly. Someone who had &#8220;outside dogs,&#8221; and who was the nervous about heartworms, might also use heartworm meds or the Safeheart method during the peak heartworm months of July and August, but only if their dogs had healthy kidneys and livers. They should make any decision with a knowledgeable vet.</p>
<p>Dr. Will Falconer, a holistic vet certified in acupuncture and homeopathy, has written an e-book called &#8220;<a href="http://www.alt4animals.com/heartworm.htm">Drug-Free Heartworm Prevention Program</a>.&#8221;  This 9-page, well-written e-book (currently $9.95) is delivered electronically.  I do not profit from sales of this book.  Drs. Richard Pitcairn and Martin Goldstein have also written about this in their books.</p>
<p>Please leave us a comment and let us know how you liked this article. Tell us about your concerns and decisions.  If we have made any errors, please let us know so we can rectify them. And, please, tell your friends the facts behind heartworm transmission.</p>
<p>Most importantly,<span style="color: #cc0000;"> <strong>do not make decisions out of fear. Don&#8217;t let anyone, even your vet, intimidate or ridicule you. Be an educated consumer and a rabid advocate for your dog&#8217;s health.</strong></span></p>
<p><span style="color: #cc0000;"><strong>Disclaimer: </strong>The information provided here is for educational purposes only. Do not rely on this information without doing your own research including consultation with your own veterinarian.  Do not buy or fail a product for treating heartworm without evaluating it carefully. </span></p>
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<p><span style="color: #cc0000;"><span style="color: #000000;"><span style="FONT-SIZE: 7pt; LINE-HEIGHT: 115%; FONT-FAMILY: 'Verdana','sans-serif'&lt;span style=">Technorati Tags: <a onclick="pageTracker._trackPageview ('/outbound/technorati.com');" rel="tag" href="http://technorati.com/tag/heartworm">heartworm</a>, <a onclick="pageTracker._trackPageview ('/outbound/technorati.com');" rel="tag" href="http://technorati.com/tag/dogs">dogs</a>, <a onclick="pageTracker._trackPageview ('/outbound/technorati.com');" rel="tag" href="http://technorati.com/tag/dog">dog</a>, <a onclick="pageTracker._trackPageview ('/outbound/technorati.com');" rel="tag" href="http://technorati.com/tag/heartworm%20medication">heartworm medication</a>, <a onclick="pageTracker._trackPageview ('/outbound/technorati.com');" rel="tag" href="http://technorati.com/tag/heartworm%20medicine">heartworm medicine</a>, <a onclick="pageTracker._trackPageview ('/outbound/technorati.com');" rel="tag" href="http://technorati.com/tag/heartworm%20prevention">heartworm prevention</a>, <a rel="tag" href="http://technorati.com/tag/heartworm%20preventatives">heartworm preventatives</a><strong> </strong></span></span></span></p>
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		<title>Heartworm Medication Part 1: Truths, Omissions and Profits</title>
		<link>http://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/</link>
		<comments>http://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/#comments</comments>
		<pubDate>Wed, 13 May 2009 08:00:10 +0000</pubDate>
		<dc:creator>Jan</dc:creator>
				<category><![CDATA[Heartworms]]></category>
		<category><![CDATA[Pet Meds]]></category>
		<category><![CDATA[dog]]></category>
		<category><![CDATA[dog heartworm]]></category>
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		<category><![CDATA[heartworm]]></category>
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		<category><![CDATA[heartworm medicine]]></category>
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		<category><![CDATA[natural cures]]></category>
		<category><![CDATA[natural preventatives]]></category>

		<guid isPermaLink="false">http://www.dogs4dogs.com/blog/?p=198</guid>
		<description><![CDATA[Heartworm “prevention” is a major health decision for pet parents ... and also multi-billion dollar Big Business for drug companies, veterinarians, testing laboratories and on-line pharmacies. Recently, sellers of heartworm meds have started recommending year round protection. How do dogs get infestations anyway? And is this change to year round protection about dog health? Or money?]]></description>
			<content:encoded><![CDATA[<div id="attachment_208" class="wp-caption alignleft" style="width: 259px"><img class="size-medium wp-image-208" title="Heartworm and dogs" src="http://www.dogs4dogs.com/blog/wp-content/uploads/2009/04/heartworm-small-249x203.jpg" alt="Heartworms are Spread by Mosquitoes. Heartworm Meds are Spread by Fear." width="249" height="203" /><p class="wp-caption-text">Heartworms are Spread by Mosquitoes. Heartworm Meds are Spread by Fear.</p></div>
<p><span style="color: #cc0000;"><strong>It&#8217;s getting warmer outside &#8212; time for sellers of heartworm medications to start scaring you to death.</strong></span>Television and print ads, which used to push meds only during warm summer months, now urge you to keep your dog on medication year round. The question is: why the change?</p>
<p><a title="Heartworm article abstract" href="http://www.ncbi.nlm.nih.gov/pubmed/9753795">Drs. David Knight and James Lok </a>of the University of Pennsylvania School of Veterinary Medicine, addressing recommendations for year round meds, warned:  <span style="color: #cc0000;"><strong>“The practice of some veterinarians to continuously prescribe monthly chemoprophylaxis exaggerates the actual risk of heartworm transmission in most parts of the country and unnecessarily increases the cost of protection to their clients.” </strong></span></p>
<p>So, is the change to year round meds all about money? Or is there more to this story?</p>
<p>Heartworm “prevention” is a major health decision for pet parents <em>and</em> multi-billion dollar Big Business for drug companies, veterinarians, testing laboratories and on-line sellers of medication. When health intersects money, there&#8217;s a lot of room for conflict of interest. Only by understanding the business aspects and the truth about heartworm transmission can you make an informed decision about if, how and when to protect your dog with commercial products.</p>
<p>While everyone agrees that heartworm infestations can be life-threatening, infestation is far from inevitable nor is it the immutable death sentence advertisers would have you believe. (Otherwise, all dogs and cats not on meds would die of infestation. But they don&#8217;t.)</p>
<p>Every holistic vet I&#8217;ve consulted had concerns about the long-term safety of heartworm <em>medications</em>. Well-known vet, author and columnist Martin Goldstein wrote in his wonderful book <em>The Nature of Animal Healing</em> that he sees heartworms as less epidemic than the &#8220;disease-causing toxicity&#8221; of heartworm medicine.</p>
<p><a href="http://www.homeovet.net/content/lifestyle/section4.html">Dr. Jeff Levy</a>, vet and homeopath, concluded “that it was not the heartworms that caused disease, but the other factors that damaged the dogs&#8217; health to the point that they could no longer compensate for an otherwise tolerable parasite load.” Those factors include, “… being vaccinated yearly, eating commercial dog food, and getting suppressive drug treatment for other symptoms….”</p>
<p><a href="http://www.homeovet.net/content/lifestyle/section4.html"></a></p>
<p>Heartworm meds do not, by the way, prevent heartworms. They are poisons that <em>kill</em> heartworm larvae (called microfilariae) contracted during the previous 30-45 days (and maybe longer due to what is call the <a href="http://en.wikipedia.org/wiki/Heartworm">Reach Back Effect</a>).</p>
<p>The heartworm industry authority, <a href="http://www.heartwormsociety.org/#">The American Heartworm Society </a>(and their <a href="http://www.knowheartworms.org/index.asp">cat heartworm site</a>) offers a wealth of information. Their website is a public service <em>but also </em>a marketing tool aimed at buyers and resellers of heartworm meds. Sponsors of this website are a Who’s Who of drug companies. Fort Dodge Animal Health (Wyeth), Merial and Pfizer are “Platinum Sponsors.” Bayer merits Silver. Novartis, Schering-Plough, Virbac and Eli Lilly get Bronze. Most of these companies have sales reps that regularly call on vets and show them how to sell you heartworm meds. With any purchase of any drug, we recommend you ask for information regarding possible adverse effects, the necessity for taking this drug and available alternatives.</p>
<p><span style="color: #cc0000;"><strong>How Heartworms Infect Dogs: It&#8217;s Not Easy!</strong></span></p>
<p>Well, now that we&#8217;ve looked behind the scenes of the heartworm <em>industry</em>, let&#8217;s take a look at how the heartworms themselves (called Dirofilaria immitis) do business. Seven steps <em>must</em> be completed to give your dog a dangerous heartworm infestation:<strong><br />
</strong><span id="more-198"></span></p>
<p>Step 1: To infect your dog, you need mosquitoes (so you need warm temperatures and standing water). More specifically, you need a hungry <em>female</em> mosquito of an <a href="http://www.heartworm-hotline.org/faq.htm "><em>appropriate species</em></a>. Female mosquitoes act as airborne incubators for premature baby heartworms (called microfilariae). Without the proper mosquito, dogs can’t get heartworms. Period.</p>
<p><strong>That means dogs can’t “catch” heartworms from other dogs or mammals or from dog park lawns. Puppies can&#8217;t “catch” heartworms from their mothers <em>and moms </em>can&#8217;t pass heartworm immunity to pups.</strong></p>
<p>Step 2: Our hungry mosquito needs access to a dog already infected with <em>sexually mature</em> male <em>and</em> female <span style="font-family: Verdana;">heartworms</span><span style="font-family: Verdana;"> that have produced babies. </span></p>
<p>Step 3: The heartworm babies must be at the L1 stage of development<em> </em>when the mosquito bites the dog and withdraws blood.</p>
<p>Step 4:  Ten to fourteen days later &#8212; if the temperature is right &#8211;the microfilariae mature<em> inside</em> the mosquito to the infective L3 stage then migrate to the mosquito’s mouth. (Yum!)</p>
<p>Step 5:  Madame mosquito transmits the L3&#8217;s to <em>your</em> dog&#8217;s skin with a bite. Then, if all conditions are right, the L3&#8217;s develop in the skin for three to four months (to the L5 stage) before making their way into your dog&#8217;s blood.  But your dog still isn&#8217;t doomed.</p>
<p>Step 6:   Only if the dog’s immune system doesn&#8217;t rid the dog of these worms do the heartworms develop to adulthood.<a href="http://www.homeovet.net/content/lifestyle/section4.html"> </a></p>
<p>Step 7:   It takes approximately six months for the surviving larvae to achieve maturity. At this point, the adult heartworms may produce babies if there are both males and females, but the kiddies will die unless a mosquito carrying L3&#8217;s intervenes.  Otherwise, the adults will live several years then die.</p>
<p>In summation, a particular species of mosquito must bite a dog infected with circulating L1 heartworm babies, must carry the babies to stage L3 <em>and </em>then must bite your dog . The adult worms and babies will eventually die off in the dog unless your dog is bitten again!  Oh, and one more thing.</p>
<p><span style="color: #cc0000;"><strong>Heartworms Development Requires Sustained Day &amp; Night Weather Above 57˚F</strong></span></p>
<p>In Step 4 above I wrote that heartworm larvae develop “if the temperature is right.”</p>
<p>The University of Pennsylvania vet school (in a <a title="UPenn Study" href="http://cal.vet.upenn.edu/projects/merial/Nematodes/nems_6d.htm ">study</a> funded by Merial) found: “Development in the mosquito is temperature dependent, requiring approximately two weeks of temperature at or above 27C (80F). Below a threshold temperature of 14C (57F), development cannot occur, and the cycle will be halted. As a result, transmission is limited to warm months, and duration of the transmission season varies geographically.”</p>
<p>Knight and Lok agree: “In regions where average daily temperatures remain at or below about 62˚F (17˚ C) from late fall to early spring, insufficient heat accumulates to allow maturation of infective larvae in the intermediate host [the mosquito], precluding transmission of the parasite.”</p>
<p>The <a href="http://www.vetmed.wsu.edu/whatsnew/HW06.asp ">Washington State University </a>vet school reports that laboratory studies show that maturation of the worms requires &#8220;the equivalent of a steady 24-hour daily temperature in excess of 64°F (18°C) for approximately one month.&#8221;  In other words, it has to be warm day AND night or development is retarded even if the <em>average </em>temperature is sufficiently warm. They add, that at 80° F, &#8220;10 to 14 days are required for development of microfilariae to the infective stage.”</p>
<p><a href="http://www.heartworm-hotline.org/faq.htm   ">Jerold Theis</a>, DVM, PhD, says, “If the mean monthly temperature is only a few degrees above 14 degrees centigrade [57 degrees F] it can take so many days for infective larvae to develop that the likelihood of the female mosquito living that long is remote.&#8221;</p>
<p>I have never found this temperature-dependent information on a website promoting &#8220;preventatives,&#8221; but only in more scholarly works not easily accessed by the public. There is, as far as I can find, only one mention of temperature on the Heartworm Society (on the <a href="http://www.heartwormsociety.org/article_1143.html">canine heartworm page</a>) and none in the Merck/Merial Veterinary Manual site or Merial&#8217;s heartworm <a href="http://www.heartwormsociety.org/article_59.html">video</a> &#8212; even though Merial funded the UPenn study.</p>
<p>The <a href="http://www.heartwormsociety.org/article_1140.html#q19">Society</a> also reports, “Factors affecting the level of risk of heartworm infection include the climate (temperature, humidity), the species of mosquitoes in the area, presence of mosquito breeding areas and presence of animal reservoirs (such as infected dogs or coyotes).”</p>
<p>******</p>
<p><span style="color: #cc0000;"><strong>Read Part 2 of this article: <a href="http://www.dogs4dogs.com/blog/2009/06/16/heartworm-preventative-options/">Heartworm Preventative Options</a> Learn how to reduce the number of times you give &#8220;preventatives,&#8221; about the little-known FDA approved low-dose preventative, and what to do if you don&#8217;t want to give meds at all. </strong></span> If you&#8217;re considering using the 6-month remedy ProHeart6, please read our previous blog post: <a title="Heartworm Protection: Do We Need ProHeart 6?" rel="bookmark" href="http://www.dogs4dogs.com/blog/2009/01/08/pesticides-poisoning-pets/">Heartworm Protection: Do We Need ProHeart 6?</a> You might also like reading <a title="Pesticides &amp; Preventatives Poisoning Pets?" rel="bookmark" href="http://www.dogs4dogs.com/blog/2009/01/08/pesticides-poisoning-pets/">Pesticides &amp; Preventatives Poisoning Pets?</a></p>
<p>Sign up for notification of  <a title="Sign up for Truth4Dogs" href="http://feeds.feedburner.com/Truth4dogs">future articles</a> and our free <a title="Sign up for our newsletter" href="http://www.dogs4dogs.com/signup">dog care e-newsletter</a> (delivered quarterly). Follow <a title="Sign up at Twitter" href="http://www.twitter.com/k9author">K9Author</a> at Twitter.</p>
<p>Please leave us a comment and let us know how your thoughts or questions regarding heartworm prevention.</p>
<p><span style="font-size: 8pt; line-height: 115%; font-family: 'Verdana','sans-serif'&lt;span style=;">Technorati Tags: <a rel="tag" href="http://technorati.com/tag/heartworm">heartworm</a>, <a rel="tag" href="http://technorati.com/tag/dogs">dogs</a>, <a rel="tag" href="http://technorati.com/tag/dog">dog</a>, <a rel="tag" href="http://technorati.com/tag/heartworm%20medication">heartworm medication</a>, <a rel="tag" href="http://technorati.com/tag/heartworm%20preventative">heartworm preventative</a>, <a rel="tag" href="http://technorati.com/tag/heartworm%20prevention">heartworm prevention</a></span></p>
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		<title>Lowering Vet Bills: 10 Tips for Keeping Costs Down</title>
		<link>http://www.dogs4dogs.com/blog/2008/12/11/vetbills/</link>
		<comments>http://www.dogs4dogs.com/blog/2008/12/11/vetbills/#comments</comments>
		<pubDate>Thu, 11 Dec 2008 18:26:09 +0000</pubDate>
		<dc:creator>Jan</dc:creator>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Dog Teeth Cleaning]]></category>
		<category><![CDATA[Heartworms]]></category>
		<category><![CDATA[Nutrition]]></category>
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		<guid isPermaLink="false">http://www.dogs4dogs.com/blog/?p=39</guid>
		<description><![CDATA[The cost of vet care for 2008 is estimated at $10.9 billion, up almost a billion from last year. With the economy tanking, jobs disappearing and the stock market down, lots of us are postponing or foregoing dog care because we can't afford treatment. It's time--past time!--to cut out unnecessary, and even harmful, products and services too many pet parents are using. Here are some <strong>cost-saving ideas that will also make dogs healthier.]]></description>
			<content:encoded><![CDATA[<p>The cost of vet care for 2009 is estimated at $12.2 billion, up $1.1 billion from last year. With the economy still ailing, jobs still disappearing and the stock market way down from previous highs, many of us are postponing or foregoing dog care because we can&#8217;t afford treatment. It&#8217;s time &#8212; past time! &#8212; to cut out those unnecessary products and services too many pet parents think are essential &#8212; but may actually be harmful. Here are some cost-saving ideas that will also make your dog healthier:</p>
<p><strong>1. STOP VACCINATING UNNECESSARILY!</strong> No more vaccinating against diseases your dog is unlikely to catch and against diseases to which your dog is already immune. Not only is unnecessary vaccination a huge waste of time and money, the resulting adverse health consequences can ruin doggy health and cost you a fortune in vet bills down the line. Watch our video <a href="http://www.dogs4dogs.com/shots">Vaccinating Dogs</a> for suggestions, and read or reread &#8220;Rethinking Vaccination&#8221; in our book, <em><a href="http://www.dogs4dogs.com">Scared Poopless</a></em>. Also, read our blog article on titer testing. (<a href=" http://www.dogs4dogs.com/blog/category/titertesting/">Click here</a>.) This simple blood test is especially important to prevent over-vaccinating puppies.</p>
<p><strong>2. FEED QUALITY FOOD.</strong> <span id="more-39"></span>Although spending more for high quality food may seem a strange way to save money, it is your absolute best shot at long-term doggy health and lower vet bills. Start feeding wisely and you may see allergies, intestinal problems, joint ouchiness and other ailments disappear. At the very least, stop feeding grocery store brands and switch from kibble to canned. Better yet, feed frozen raw or fresh cooked or raw. My book has two chapters on food, one of them you can read free by clicking <a href="http://www.dogs4dogs.com/JR_PDFs%20from%20Book/FoodtoDieFor.pdf"> here</a>.</p>
<p><strong>3. FEED LESS.</strong> According to Purina&#8217;s much promoted 14-year study of 48 Labrador Retrievers, &#8220;lean-fed&#8221; dogs (receiving 25% less food than their littermates) eventually developed the same health problems as littermates as they aged, but needed treatment for ailments 2.1 years later. That is, treatment began at a mean age of 12 versus age 9.9.  Here&#8217;s the secret to longevity: It&#8217;s not about feeding a particular brand; it&#8217;s about feeding to a healthy, lean (not too skinny) condition. Cut out all fattening corn-laden foods. Don&#8217;t leave food out all day and don&#8217;t overfeed. Remember: fat dogs aren&#8217;t cute; they&#8217;re expensive.</p>
<p><strong>4. BRUSH TEETH MORE OFTEN.</strong> Few things are more expensive, or risky, than dental procedures. Avoid them by feeding low-carb foods (not kibble) and by brushing your dog&#8217;s teeth at least three times a week. Use a good paste meant for dogs (not Humans!) and use gauze around your finger or a super-soft toothbrush.</p>
<p><strong>5. STOP GIVING UNNECESSARY OR DANGEROUS DRUGS. <strong> </strong></strong>Check out your dogs meds (especially steroids and arthritis medications) on-line by name, and at the websites listed under <a href="http://www.dogs4dogs.com/links.html">Preventing the Preventable</a> on my website link page. Also, if it&#8217;s not mosquito season where you live, why are you giving heartworm meds? No skeeters &#8230; no heartworm. Fleas aren&#8217;t much of a problem during the winter in most places either. Check out my book&#8217;s chapter, &#8220;Stop Pest-ering Me!&#8221; or do research on-line to learn more about heartworm and flea life cycles and natural methods of pest control. Just make sure your research is from reliable, unbiased sources. Websites that look &#8220;scientific&#8221; may be fronts for manufacturers of pet meds. Also check out my blog post on <a href="http://www.dogs4dogs.com/blog/category/pet-meds/heartworms/">Heartworms</a> for more information about protection.</p>
<p><strong><strong><strong>6. GET FLUFFY A BLOOD TEST</strong> </strong></strong>if she hasn&#8217;t had one in the last year (or six months for senior dogs). Remember, dogs age faster than we do and a thorough blood test (with a chem panel) is the easiest (and sometimes the only) way to detect disease while it&#8217;s still curable and cheaper to treat. Also test yearly for heartworms, whether or not you use meds.</p>
<p><strong><strong><strong>7. STOP GIVING DANGEROUS TREATS</strong> </strong></strong>that can perforate or lodge in tracheas and intestines: cooked bones,  rawhide chews, pig’s feet and other too-hard chews.  Surgery for obstructions and perforations is very expensive and may come too late to save your dog&#8217;s life.</p>
<p><strong><strong><strong>8. WASH YOUR DOG’S FEET</strong> </strong></strong>after a walk on chemically-laden surfaces like city streets and salted roads. Beware park areas which may have been recently fertilized, or treated with herbicides, without your knowing. And don’t use toxic chemicals in your home or yard.  If it’s on your dog’s feet, before long it will be in your dog’s mouth. If it&#8217;s in your dog&#8217;s mouth, he&#8217;s on the slippery slope toward cancer.</p>
<p><strong><strong><strong>9. SECURE TRASH, RECYCLING BINS AND TOXIC CHEMICALS FROM PETS. </strong></strong></strong>You&#8217;d be shocked at how much money is spent on inadvertent poisoning from snail, ant and rat bait, and also the general ailment called &#8220;Garbage Can Syndrome.&#8221; (Thanks to Pet Evironmentalist Elizabeth Allen of <a href="http://C4PAW.com">C4PAW.com</a> for her work in this area.)</p>
<p><strong><strong><strong><strong>10. RESEARCH ON-LINE HELP. </strong></strong></strong></strong>Check out the additional cost saving ideas at the Human Society (<a href="http://www.hsus.org/pets/pet_care/what_you_can_do_if_you_are_having_trouble_affording_veterinary_care.html ">click here</a>) and  in the Smart Money article (<a href="http://www.smartmoney.com/spending/deals/cut-those-doggone-vet-bills-19053/">click here</a>). Californians, e-mail Governor Schwarzenegger and tell him we can&#8217;t afford his new 9% tax on our vet bills! <a href="https://secure2.convio.net/aspca/site/Advocacy?pagename=homepage&amp;page=UserAction&amp;id=2445&amp;JServSessionIdr005=oz2jjbisg1.app23b">Click here</a>.</p>
<p>In short, think before you spend. Ask questions. Don&#8217;t automatically reorder drugs. Consider alternatives. Become an educated consumer and trust your own instincts.</p>
<p>Looking for smart holiday gifts and more health and safety tips for your dog? <a href="http://www.dogs4dogs.com/JR_Articles/Holiday2008.html">Click here to read our Holiday Newsletter.</a></p>
<p>Sign up for notification of  <a title="Sign up for Truth4Dogs" href="http://feeds.feedburner.com/Truth4dogs">future articles</a> and our free <a title="Sign up for our newsletter" href="http://www.dogs4dogs.com/signup">dog care e-newsletter</a> (delivered quarterly). Follow <a title="Sign up at Twitter" href="http://www.twitter.com/k9author">K9Author</a> at Twitter.</p>
<p>Cross post this article with attribution. <a href="http://www.dogs4dogs.com/blog/legal-stuff/">Click here</a> for details.<br />
<a rel="me" href="http://technorati.com/claim/ww7yw7yc9x"><br />
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		<title>Heartworm Protection: Do We Need ProHeart 6?</title>
		<link>http://www.dogs4dogs.com/blog/2008/06/18/your-dogs-heartworm-protection-do-we-need-proheart-6/</link>
		<comments>http://www.dogs4dogs.com/blog/2008/06/18/your-dogs-heartworm-protection-do-we-need-proheart-6/#comments</comments>
		<pubDate>Wed, 18 Jun 2008 18:06:45 +0000</pubDate>
		<dc:creator>Jan</dc:creator>
				<category><![CDATA[Heartworms]]></category>
		<category><![CDATA[Pet Meds]]></category>
		<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[adverse reactions]]></category>
		<category><![CDATA[dogs]]></category>
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		<category><![CDATA[Fort Dodge]]></category>
		<category><![CDATA[heart worm]]></category>
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		<category><![CDATA[medication]]></category>
		<category><![CDATA[ProHeart 6]]></category>
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		<description><![CDATA[ProHeart 6, a heartworm “preventative” shot providing 6 months of protection against canine heartworms, is back on the market after having been pulled from shelves in 2004 by manufacturer Fort Dodge. More than 5,000 adverse “events,” including hundreds of canine deaths, prompted the FDA to request the drug’s withdrawal. I wonder, why is ProHeart 6 so indispensable that it must be brought back? If so, who wins? Who loses?]]></description>
			<content:encoded><![CDATA[<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">ProHeart 6, a heartworm “preventative” shot providing 6 months of protection against canine heartworms, is back on the market after having been pulled from shelves in 2004 by manufacturer Fort Dodge. More than 5,000 adverse “events,” including hundreds of canine deaths, prompted the FDA to request the drug’s withdrawal. It is being brought back under a &#8220;risk minimization action plan&#8221; and restricted use program (including vet training and informed consent notification) &#8212; an uncommon plan to try to limit damage from the drug.<br />
</span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">I wonder, why is ProHeart 6 so indispensable that it must be brought back? <span id="more-19"></span>There are safer once-a-month heartworm “preventatives.” More importantly, there are countless natural, non-toxic alternatives. (<span style="color: black;">By the way, heartworm drugs do not “prevent” heartworms. They kill them.)<br />
</span></span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">Does a risky six-month remedy have any real value? Not to me as loving guardian to two dogs, and certainly not to the dogs themselves who may suffer potentially lethal adverse reactions. The main value will be to Fort Dodge stockholders and to the vets who benefit from the sale of the product plus the office visit to give the shot.</span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">Before writing about heartworms and other parasites for my <a title="Scared Poopless" href="http://www.Dogs4Dogs.com">book</a>, <em>Scared Poopless: The Straight Scoop on Dog Care,</em> <span style="color: black;">I interviewed three veterinarian-authors and two other holistic vets, and also spent months reading and doing on-line research. Every vet I consulted thought heartworm medications were toxic. Dr. Martin Goldstein, renowned veterinary and author, has written that he sees heartworms as less of an epidemic than the &#8220;disease-causing toxicity&#8221; of heartworm medicine. </span></span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">No discussion of this medicine would be complete without a study of the heartworm life cycle. Microfilariae, which grow into heartworms, must be injected into dogs by female mosquitoes. </span><span style="font-size: 10pt; line-height: 115%; font-family: ">No mosquitoes, no heartworm infestation. </span><span style="font-size: 10pt; line-height: 115%; font-family: ">Dogs with poor diets, and those suffering from immune system dysfunction, are particularly susceptible.<br />
</span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">Most U.S. locales don&#8217;t have mosquitoes in cold weather. But even if mosquitoes are present, according to the University of Pennsylvania vet school, microfilariae require sustained periods of weather above 80 degrees and not below 57 degrees (Fahrenheit) to develop to the proper stage to be delivered. </span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">Thus, protection against heartworms is unnecessary year round in many locations. Read more about the mosquito’s life cycle at a website owned by ProHeart manufacturer Fort Dodge, click <a title="Heartworm Society" href="http://www.heartwormsociety.org/heart.htm">here</a>. For an unbiased look at nationwide incidences of heartworm and drug adverse reactions, click </span><span style="font-size: 11pt; line-height: 115%; font-family: "><a href="http://www.dogsadversereactions.com/moxidectin/heartwormmaps.html"><span style="font-size: 10pt; line-height: 115%; font-family: ">www.dogsadversereactions.com/moxidectin/heartwormmaps.html</span></a></span><span style="font-size: 10pt; line-height: 115%; font-family: "> </span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">I live in Southern California, an arid area with few heartworm cases. For my own dogs, I use non-toxic alternatives: natural non-toxic bug repellent and keeping the dogs indoors when mosquitoes are buzzing. I also make sure there is no standing water in my yard. </span></p>
<p class="MsoNormal"><span style="font-size: 10pt; line-height: 115%; font-family: ">I increase safety by testing my dog’s blood once yearly for heartworm antigens, something also required if they were to take heartworm “preventatives.”<span> </span>If I lived in an area with sustained hot weather and lots of mosquitoes, I’d test twice yearly. Heartworm infestation is generally curable when caught early. The current canine movie star “Benji” is a heartworm survivor.</span></p>
<p class="MsoNormal"><strong> *******</strong></p>
<p class="MsoNormal">A follow-up: Still considering giving your dog ProHeart 6 for heartworm protection? ProHearts’ own Client Information Form lists adverse reactions: &#8220;These can include (but are not limited to) allergic responses, lethargy (sluggishness), seizures, vomiting and diarrhea, itching at the injection site, fever and, in rare instances, death.&#8221; <!--more-->Read the entire <a title="Proheart 6" href="www.proheart6.com/Pdfs/PH6ClientInfo.pdf ">Proheart form</a> at (Note: To enlarge the print size, change it to &#8220;100%&#8221; on the toolbar underneath the word &#8220;Help.&#8221;)<a href="http://www.proheart6.com/Pdfs/PH6ClientInfo.pdf"><br />
</a></p>
<p class="MsoNormal">An article from the FDA worth reading reports &#8220;the side effects&#8230;anorexia (loss of appetite); lethargy; vomiting; neurologic signs, such as seizures, difficulty walking and reports of blindness; jaundice (a yellowish appearance); and bleeding disorders. Most of these observable clinical signs have occurred within one month of receiving the drug.&#8221; <a title="FDA on Vaccines" href="http://www.fda.gov/cvm/PH6QA.htm ">www.fda.gov/cvm/PH6QA.htm </a></p>
<p class="MsoNormal" style="margin-bottom: 0.0001pt; line-height: normal;"><span style="font-size: 10pt; font-family: ">To comply with the FDA&#8217;s &#8220;risk minimization&#8221; plan, Fort Dodge is implementing an educational and communication program that will require veterinarians to register with Fort Dodge and complete &#8220;in-depth&#8221; training as a condition of purchasing ProHeart 6. A letter from the FDA explains vets will also have to &#8220;confirm they have completed the in-depth training, read the new label, the conditions of use, the requirements to provide the dog owner with the Client Information Sheet and obtain signed informed consent, record the product lot number in the medical record, and report adverse events. Veterinarians are also advised to obtain baseline history, physical exam, and blood-work parameters prior to administration of the drug to confirm the patient is an appropriate candidate for ProHeart 6.&#8221; Read the entire letter at</span><span style="font-family: "> </span><a href="http://www.fda.gov/cvm/ProHeart6AVMA.htm">http://www.fda.gov/cvm/ProHeart6AVMA.htm</a></p>
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<p class="MsoNormal" style="margin-bottom: 0.0001pt; line-height: normal;"><strong>In-depth heartworm articles: </strong></p>
<p><a href="http://www.dogs4dogs.com/blog/2009/06/16/heartworm-preventative-options/">Heartworm Medication Part 1: Truths, Omissions and Profits<br />
Heartworm Medication Part 2: Options to Fear-Based Recommendations</a></p>
<p><a href="http://www.dogs4dogs.com/blog/2009/05/13/heartworm-medication-safety/"></a></p>
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